校閲者・コーディネーターの月替わりのコラム

2019.3.5 Editor: G.S.

Similarities and differences between scientific abstracts for journals and conferences: An example

In last month’s column, we mentioned that abstracts aimed for journal publications tend to be more detailed, whereas those intended for meetings (i.e., posters) are more concise and contain simpler language. Below we provide an example to illustrate differences between the two types of abstracts:

Introduction

Journal:The expression of the X gene has been implicated in the development of resistance in leukemia. Studies on hepatoma cell lines have shown that activation of the X gene involves the transcription factors TF1 and TF2. The objective of this study was to investigate the relevance of this model in leukemia.

Meeting:The X gene is implicated in the development of resistance in leukemia. We investigated the role of transcription factors TF1 and TF2 in the activation of the X gene in leukemic cell lines.

Methodology

Journal:Human leukemic cell lines (LE1 and LE2) were subjected to deprivation conditions mimicking the effects of treatment for 12 hours. The treatment included growth in medium lacking the nutrients A and B. Subsequently, we determined the mRNA and protein levels of TF1 and TF2 using real-time reverse transcription quantitative polymerase chain reaction and western blotting.

Meeting:LE1 and LE2 cells were cultured in medium for 12 hours under nutritional deprivation (i.e., lacking A and B). Real-time reverse transcription quantitative polymerase chain reaction and western blotting were used to determine the mRNA and protein levels of TF1 and TF2.

Results

Journal:After 12 hours of nutritional deprivation, LE1 cells exhibited only minor increases in the mRNA and protein levels of the transcription factors TF1 and TF2 compared with baseline. Similarly, in LE2 cells, the observed increases in the mRNA and protein levels of TF1 and TF2 after 12 hours of nutritional deprivation were not significant.

Meeting:In both cell lines, the mRNA and protein levels of the transcription factors TF1 and TF2 did not change significantly after 12 hours of nutritional deprivation.

Conclusions

Journal:This evidence suggests that TF1 and TF2 are not involved in the activation of the X gene in leukemia following nutritional deprivation. These results suggest the involvement of additional factors in the development of resistance in leukemia.

Meeting:TF1 and TF2 are not involved in the activation of the X gene in leukemia following nutritional deprivation. Additional factors may be involved in the development of resistance in leukemia.

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